Know what changed and why it matters.

Protocol Amendment Comparison turns a hundred-page redline into a prioritized, citable review — so your team spends time making decisions, not hunting for changes.

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See How it Works

Know what changed and why it matters, in minutes.

Protocol Amendment Comparison turns a hundred-page redline into a prioritized, citable review — so your team spends time making decisions, not hunting for changes.

Book a Demo

See How it Works

Know what changed and why it matters, in minutes.

Protocol Amendment Comparison turns a hundred-page redline into a prioritized, citable review — so your team spends time making decisions, not hunting for changes.

Book a Demo

See How it Works

Amendment review shouldn't cost your team a week

Protocols routinely run past a hundred pages. When an amendment lands, research teams are left comparing versions line by line, with no way to tell a critical eligibility change from a typo fix until they've read the whole thing.

"Finding changes takes too long."

Manual side-by-side comparison of long protocols eats days that should go to trial decisions.

"Need AI to prioritize changes."

Without prioritization, a contact-detail fix gets the same attention as a dosing change.

"Need AI to prioritize changes."

Without prioritization, a contact-detail fix gets the same attention as a dosing change.

"Hard to know what is important."

Teams need to trust what an amendment changed — and be able to prove it during an audit.

One workspace, three levels of detail

Start with the big picture. Go as deep as the decision requires, and never lose the thread back to the source document.

Overview by Severity
1
Sections

  • Eligibility Criteria

  • Dosing Schedule

  • Visit Schedule

  • Informed Consent

  • Administrative (24)

Critical changes surface first, always.

Cited AI Summary
2
Eligibility - age range narrowed

The upper age limit for enrollment was reduced from 65 to 55 years to align with updated safety data.

Source: 4.2.1 Inclusion Criteria

Exact inline redline
3
Eligibility - age range narrowed

Subjects aged 18 to

65

to

67

years with a confirmed diagnosis, able

years with a confirmed

years

to provide written informed consent prior to any study procedure.

diagnosis, able to provide written informed consent prior to any study procedure.

with a confirmed diagnosis, able to

to provide written informed consent prior to any study procedure.

Stop reading amendments line by line.

See Protocol Amendment Comparison on your own protocols.

Schedule a Walkthrough

How it works

How it works

From protocol to source documents in minutes

How to Compare Protocol Amendments in Clinials | Protocol Comparison

How it works

From protocol to source documents in minutes

How to Compare Protocol Amendments in Clinials | Protocol Comparison
  1. Upload the Protocol

Clinials analyses the protocol structure and Schedule of Activities.

2. Select a visit

Generate forms for Screening, Baseline, Treatment, Post-Treatment visits, Follow-Up, or Unscheduled visits.

  1. Generate Forms

Clinials creates visit-specific source documents and worksheets.

  1. Download and Edit

Export forms as DOCX or PDF for site use.